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Immunotherapeutics: Advancing precision medicine in cancer treatment

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Author Details : Chhatrola Savan*, Arun Vaghela, Ishita Zalavadiya, Keval Raval

Volume : 9, Issue : 1, Year : 2024

Article Page : 17-23

https://doi.org/10.18231/j.ijcaap.2024.003

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Abstract

Immunotherapy, also known as biologic therapy or biotherapy, is a medical treatment that utilizes the immune system to combat diseases, including cancer. Over the past few decades, immunotherapy has emerged as an integral part of cancer treatment, with various approaches being explored. This article provides an overview of immunotherapy, its mechanisms of action, and the different types of immunomodulators involved. Activation immunotherapies aim to enhance the immune response, such as cancer vaccines and cellular therapies, while suppression immunotherapies work to reduce or suppress immune activity. The article also discusses the different types of immunotherapies, including cell-based immunotherapies, immunomodulators, vaccines, antibody-based targeted therapies, and oncolytic viruses. Additionally, it highlights the characteristics of an ideal immunomodulator and the limitations associated with these therapies. Monoclonal antibodies, both naked and conjugated, are explored as a specific type of immunotherapy, with examples of their use in treating various cancers. Furthermore, the article touches upon the classification and uses of immunosuppressive agents, particularly in organ transplantation, along with their adverse effects. Overall, this article provides a comprehensive overview of immunotherapy and its diverse applications in disease treatment.

Keywords: Immunotherapy, Immunomodulators, Monoclonal Antibodies

How to cite : Savan C, Vaghela A, Zalavadiya I, Raval K, Immunotherapeutics: Advancing precision medicine in cancer treatment. IP Int J Compr Adv Pharmacol 2024;9(1):17-23

This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.