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Exploring the possibility for neurobehavioural impairment of aqueous ethanolic extracts of leaf/seed of asparagus racemosus, Anogeissus latifolia Roxb, and Phyllanthus niruri growing on ipomoea carnea tree in mice

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Original Article

Author Details : Anubhav Dubey*, Mamta Kumari, Manu Dwivedi, Niladry S Ghosh, Debashis Tripathy

Volume : 8, Issue : 4, Year : 2023

Article Page : 256-264

https://doi.org/10.18231/j.ijcaap.2023.041

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Abstract

This study aimed to investigate the liability and extracts of some medicinal plants for some neurobehavioural toxicities in mice. The results indicate, compared to negative control (distilled water) treatment mean values of 4.69±0.95 % locomotory activity reduction, 430.71±16.80 sec. sleep onset and 168.43±10.56 min. duration, 5.00±0.00 balance/motor co-ordination performance, and 54.41±1.99 novel object recognition, treatments with high oral doses of Phyllanthus niruri and Asparagus racemosus (1500 mg/kg each) did not significantly negatively impact these behavioural indices but even enhanced novel object recognition. High oral doses of Anogeissus latifolia Roxb and Ipomoea carnea (750 mg/kg each), and tramadol (133 mg/kg) caused significant (p<0>  

Keywords: Actophotometer, Evaluation, Mouse, Asparagus racemosus, Anogeissus latifolia Roxb, Phyllanthus niruri, Ipomoea carnea

How to cite : Dubey A, Kumari M, Dwivedi M, Ghosh N S, Tripathy D, Exploring the possibility for neurobehavioural impairment of aqueous ethanolic extracts of leaf/seed of asparagus racemosus, Anogeissus latifolia Roxb, and Phyllanthus niruri growing on ipomoea carnea tree in mice. IP Int J Compr Adv Pharmacol 2023;8(4):256-264

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