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Oxidative stress and neurodegenerative diseases: Exploring natural antioxidants for therapeutic potential

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Review Article

Author Details : Santosh Kallur, Aditya Suryawanshi, Akshada Utarade, Pallavi Kandalkar, Rushikesh Morde, Ajay Bhagwat, Rohit Doke*

Volume : 8, Issue : 3, Year : 2023

Article Page : 149-158

https://doi.org/10.18231/j.ijcaap.2023.026

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Abstract

Neurodegenerative diseases, including Alzheimer's, Parkinson's, and Huntington's, are a growing global health challenge with no definitive cure. Oxidative stress is implicated in these disorders, and antioxidants have emerged as a promising avenue for addressing them. Research has shown the potential of natural antioxidants to combat oxidative stress in neurodegenerative disorders, but clinical trials have often failed to treat patients effectively. However, natural extracts have shown diverse molecular activities beyond their antioxidant capabilities, indicating their potential for prevention and disease management. This review will explore in vitro and in vivo research studies to highlight the promising prospects of natural antioxidants and their therapeutic applications in Neurodegenerative conditions.
 

Keywords: Parkinson's Disease, Alzheimer's Disease, Huntington's Disease, Oxidative stress, Natural antioxidants

How to cite : Kallur S, Suryawanshi A, Utarade A, Kandalkar P, Morde R, Bhagwat A, Doke R, Oxidative stress and neurodegenerative diseases: Exploring natural antioxidants for therapeutic potential. IP Int J Compr Adv Pharmacol 2023;8(3):149-158

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