Print ISSN:-2581-5555
Online ISSN:-2456-9542
CODEN : IIJCDU
Review Article
Author Details :
Volume : 8, Issue : 1, Year : 2023
Article Page : 22-26
https://doi.org/10.18231/j.ijcaap.2023.003
Abstract
Spinal muscular atrophy is an inherited neurodegenerative illness characterized by muscle wasting and loss of spinal cord motor neurons. It results from homozygous loss, translation, or mutation of the survival motor neuron 1 (SMN1) gene. Despite the lack of a cure, research has revealed potential processes explaining the disease’s molecular etiology. The SMN1 gene region’s distinctive genomic structure has been used to design treatment plans. Several stages of development have been recognized for a number of possible therapeutic agents. The standard of treatment for people having spinal muscular atrophy has evolved as a result of these and other healthcare technological advancements. In this review, we provide a comprehensive review of general introduction, types, symptoms, causes, diagnosis, and possible management of spinal muscular atrophy (SMA)..
Keywords: Spinal muscular atrophy, Inherited, Muscle biopsy, Mutation, Electrodiagnosis
How to cite : Dwivedi M, Mishra A, Singh M, Singh N, Tripathi A, Singh C P, A review on spinal muscular atrophy: An inherited neuromuscular disease. IP Int J Compr Adv Pharmacol 2023;8(1):22-26
This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.