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An observational study on patient compliance and adverse drug reactions of antihypertensives drugs in a tertiary care center of Bihar

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Original Article

Author Details : Kumar Gaurav, Mrityunjay Kumar Pandit*, Jeetendra Kumar

Volume : 6, Issue : 4, Year : 2021

Article Page : 190-193

https://doi.org/10.18231/j.ijcaap.2021.033

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Abstract

Introduction: Hypertension is among the most common non-communicable and lifestyle disease in our country that affects adult population of both the genders from all socio-economic backgrounds and urban and rural population. In-spite of this, early diagnosis and appropriate treatment are suboptimal. Adherence of prescribed treatment has been studied in patients of hypertension in this study.
Materials and Methods: An observational and cross-sectional study was conducted in the Department of Pharmacology, Jawahar Lal Nehru Medical College and Hospital, Bhagalpur, Bihar. Prior to the initiation of the study, clearance was obtained from the Institutional Ethics Committee. Study period was between January 2021 and June 2021.A predesigned pretested interview schedule was used to collect the data from the 247 study participants. This schedule contained information related to socio-demographic variables, comorbidity, a format to assess the compliance to antihypertensive drugs prescribed and any adverse event.
Results: A significant improvement in maintain optimal in blood pressure was observed in patients treated with one pill per day as compared to patients prescribed with two and three pills per day. Compliance was significantly better in patients in combination therapy as compared to monotherapy.
Conclusion: Low dose combination therapy has been stated to be more effective than high dose monotherapy in controlling blood pressure. It shows better compliance and lesser incidence of side-effects.
 
Keywords: Hypertension, Antihypertensive drugs, Compliance, Adverse drug reactions

How to cite : Gaurav K, Pandit M K, Kumar J, An observational study on patient compliance and adverse drug reactions of antihypertensives drugs in a tertiary care center of Bihar. IP Int J Compr Adv Pharmacol 2021;6(4):190-193

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